Protein Details: Gap junction alpha-10 protein

Protein ID

ICDB_Pro_1395

Protein Name

Gap junction alpha-10 protein

Gene Name

GJA10; CX62

Organism

Homo sapiens (Human)

Length

543 amino acids

AlphaFoldDB

AF-Q969M2-F1-model_v4.pdb

Function

Sequence

MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSKTMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSPCPWAGSAGNQHLGQQSDHSSFGLQNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLHSHCRDSEGSMRESGVWIDRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHWENSPSPLPSVTGHRTSMVRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGGGDYLWRDKIIHSIHSVKFNS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Bart-Pumphrey Syndrome and Congenital Myopathy 4A;Autosomal Dominant

Location

Expressed in skeletal muscle and heart

DOI ID

10.1515/bc.2002.076; 10.1038/nature02055; 10.1080/15419060302063

RefSeq

NP_115991.1